Sie sind hier
Institute of Technology and ManagementHealth Care Management
There is no English
translation for this web page.
|Autor||Stock S, Redaelli M,
Simic D, Siegel M, Henschel
Elderly people are especially prone to
suffer adverse drug reactions (ADR). Main reasons for the higher
vulnerability of the elderly to ADR are changes in metabolism as i.e.
slower renal clearance and polypharmacie which often results from
multimorbidity. To prevent ADR careful prescription with special
consideration of these aspects is warranted. To help physicians avoid
drugs which are especially likely to cause ADR lists have been
developed following the consensus method process. For Germany this
list is called the PRISCUS list. It was developed based on a
literature review, review of international lists such as the American
Beers list, and a consensus process based on a Delphi survey. It
contains 83 drugs from 18 classes which are classified as potentially
inapropriate medication (PIM). It also lists alternatives for each
PIM. If a drug is registered with the PRISCUS list this does not mean
automatically that it is contraindicated in the elderly but that
special caution should be excercised in prescribing the drug,
alternatives should be considered and the patient carefully
Prescription rates for PIMs in Germany in the elderly is pretty
much stable at around 23% with only a small decline in the past years.
Also, more than 5% of all prescriptions in the elderly are PIM
prescriptions. Physicians specially trained in geriatrics tend to
prescribe less PIMs compared to other physicians.
Copyright: © Springer-Verlag Wien